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Figure 4 | Retrovirology

Figure 4

From: Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection

Figure 4

Replication kinetics in primary PBMCs indicate an inability of double mutant viruses to establish spreading infection. PBMCs were infected with 0.1 and 1 ng p24 of wild-type envelope HIV-1, and virus production was measured at given time points post-infection by p24 ELISA on the culture supernatants. Results show the mean of duplicates +/- SEM for two donors.

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