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Table 2 Other HML-2 (and HML-2-like) proviruses

From: Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses

Provirus

Alias

Chr

Orientation

Start

End

Oldest Common

Ancestora

Estimated Ageg

ORFs

Reference

1p36.21a

 

1

(-)

12840260

12846364

Orangutan

N/A

gag

This Study

1p36.21c

K6,K76

1

(+)

13678850

13688242

Orangutan

22.69-41.09

gag

Hughes and Coffin, 2001

1p34.3

 

1

(-)

36955490

36956728

Orangutan

N/A

 

This Study

1q43

 

1

(-)

238925595

238927773

Rhesus

N/A

 

This Study

4p16.3b

K77

4

(-)

3980069

3988631

Chimpanzee

11.1-20.1

 

Romano et al., 2006

4p16.1b

K50c

4

(+)

9659588

9668650

Chimpanzee

17.19-31.13

 

Macfarlane and

Simmonds, 2004

5q33.2

K18b

5

(-)

154016502

154024214

Chimpanzee

13.03-23.6

env

Romano et al., 2006

6p11.2

K23

6

(+)

57623896

57628704

Orangutan

9.38-16.99

 

Romano et al., 2006

7q11.21

 

7

(-)

65469689

65472384

Chimpanzee

N/A

 

This Study

8p22

 

8

(-)

17765202

17773940

Rhesus

N/A

 

This Study

8q24.3b

K29

8

(-)

146246648

146254211

Gibbonf

12.33-22.33

env

Hughes and Coffin, 2001

12q24.33

K42

12

(-)

133667120

133673132

Orangutan

7.07-12.81

 

Romano et al., 2006

14q11.2

K(OLDAL136419),

K71

14

(-)

24480625

24484121

Orangutan

11.98-21.69

gag

Reus et al., 2001

14q32.33

 

14

(+)

106139659

106142540

Rhesus

N/A

 

Romano et al., 2006

15q25.2

 

15

(+)

84829020

84832364

Orangutan

N/A

 

This Study

16p13.3

K(OLDAC004034

16

(+)

2976160

2977661

Rhesus

N/A

 

This Study

17p13.1

 

17

(+)

7960357

7967219

Rhesus

N/A

 

This Study

19q13.41

 

19

(-)

53248274

53252591

Orangutan

N/A

pol

Hughes and Coffin, 2001

22q11.23

K(OLDAP000345),

KOLD345

22

(+)

23879930

23888810

Gorillaf

21.64-39.18*

gag

Hughes and Coffin, 2001

Xq11.1

 

X

(+)

61959549

61962054

Unknown b

N/A

env

This Study

Xq12

 

X

(-)

65684132

65686184

Human Specific c

N/A

 

This Study

Xq28a

K63

X

(+)

153817163

153819562

Human Specificd

N/A

gag

Macfarlane and

Simmonds, 2004

Xq28b

K63

X

(-)

153836675

153844015

Orangutan

14.65-26.52

gag

Macfarlane and

Simmonds, 2004

Yq11.23a

 

Y

(-)

26397837

26401035

Chimpanzee e

N/A

 

This Study

Yq11.23b

 

Y

(+)

27561402

27564601

Chimpanzee e

N/A

 

This Study

  1. aRefers to most distant species with shared provirus. Determined by searching for provirus at the corresponding locus by BLAT
  2. searching flanking sequence in the chimpanzee, orangutan, and rhesus publicly available genomes on the UCSC genome browser.
  3. bRegion is flanked by satellite DNA, no good match found in non-human primate genomes.
  4. cNo good match found in non-human primate genomes.
  5. dProvirus is a product of a duplication event post human/chimpanzee split.
  6. eProvirus is a product of a duplication event post chimpanzee/orangutan split.
  7. fFrom Hughes and Coffin, 2001.
  8. gAges based upon molecular clock calculations from Hughes and Coffin, 2005. N/A indicates unpaired LTRs or LTRs lacking sufficient sequence to determine age. Asterisk denotes age listed is for a recombinant provirus.
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Retrovirology

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