Figure 4

Maraviroc inhibition curves in differentially-induced 293-Affinofile cell populations. Luciferase reporter viruses pseudotyped with MVC-Sens, MVC-Res, YU2 or JRCSF Envs were used to infect 293-Affinofile cells induced with 2.5 ng per ml of minocycline together with increasing concentrations of ponasterone A, in the presence of increasing concentrations of MVC as described in the Methods, and virus inhibition curves were generated as described previously [15]. The data shown are means of triplicates and are representative of 3 independent experiments. Error bars represent standard error.