Figure 1

Viral RNA dynamics in macaques vaccinated with attenuated SIV. Following vaccination of cynomolgus macaques (n = 20) with live attenuated SIV plasma and lymphoid tissue viral loads was determined at days 0, 3, 7, 10, 21 and 125 post inoculation. Mean attenuated SIV RNA plasma levels peaked at day 10 with a nadir between days 84 and 125. For analysis n = 16 at day 3 reducing to n = 6 by day 21 as animals were sacrificed, n = 2 at all time points thereafter. Error bars shown are ± 1 SEM.