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Figure 1 | Retrovirology

Figure 1

From: Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys

Figure 1

APOBEC3 mRNA levels in uninfected and SIV-infected macaques. A3G (left panels) and A3F (right panels) mRNA levels were determined in uninfected (triangles) and SIV-infected animals with (diamonds) or without (circles) AIDS symptoms. Relative APOBEC3 mRNA levels are shown in copy numbers per 100 copies of GAPDH in PBMC (A, B), CD4+ T-cells (C, D), CD14+ monocytes (E, F), lymphocytes from peripheral (G, H) and mesenteric lymph nodes (I, J). Each data point represents one individual animal. Horizontal lines within the clusters are depicting the median. Group comparisons were calculated using either the Kruskal-Wallis test with Dunn's multiple comparison analysis for PBMC, CD4+ T-cells and peripheral lymph nodes or the Mann-Whitney test for CD14+ monocytes (*p < 0.05; **p < 0.001). nd, not determined; asymp., asymptomatic.

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Retrovirology

ISSN: 1742-4690

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