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Figure 2 | Retrovirology

Figure 2

From: Distinct roles of CD4+T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model

Figure 2

Distinct roles for CD4+ T cell subpopulations in chronic Friend Retrovirus infection. During chronic infection, effector CD8+ T cell responses are suppressed by regulatory T cells but a subpopulation of effector CD4+ T cells prevents virus reactivation. (Blocked lines indicate inhibition of immune responses or virus replication; the dotted line indicates that this response is suppressed during chronic infection).

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