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Figure 6 | Retrovirology

Figure 6

From: Latency profiles of full length HIV-1 molecular clone variants with a subtype specific promoter

Figure 6

LTR promoter elements of subtypes B and AE. A: The core promoter elements in the LTR of subtypes B and AE. Indicated transcription factor binding sites are: RBEIII, NFκB, GABP, Sp1 and the TATA box. BseA1 indicates the recognition site for the endonuclease used for molecular cloning. B: Percentages of CA-p24 positive cells without induction determined by FACS. C: Fold activation by TNFα induction. The results are presented as the average values of three independently produced virus stocks, each tested in two independent infections. P values: * = p < 0.05, ** = p < 0.01, *** = p < 0.001.

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