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Table 3 Genotypic prediction of HIV-1 tropism by a subtype D specific algorithm compared to the observed phenotype

From: Genotypic prediction of HIV-1 subtype D tropism

   TTT Concordance Genotypic Prediction
Genotypic tool   R5 R5X4/X4   Sena Speb
Combined 11/25 and net charge rules for subtype D R5 21 1 92% 75% 95%
  X4 1 3 κ = 0.70 (p < 0.001)   
  1. aSen: sensitivity for predicting CXCR4-using viruses
  2. bSpe: specificity for predicting CXCR4-using viruses
  3. κ: kappa coefficient.