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Table 3 Genotypic prediction of HIV-1 tropism by a subtype D specific algorithm compared to the observed phenotype

From: Genotypic prediction of HIV-1 subtype D tropism

  

TTT

Concordance

Genotypic Prediction

Genotypic tool

 

R5

R5X4/X4

 

Sena

Speb

Combined 11/25 and net charge rules for subtype D

R5

21

1

92%

75%

95%

 

X4

1

3

κ = 0.70 (p < 0.001)

  
  1. aSen: sensitivity for predicting CXCR4-using viruses
  2. bSpe: specificity for predicting CXCR4-using viruses
  3. κ: kappa coefficient.