Figure 1
Clinical data for P1 compared with that of P2. The a. CD4+ counts (/mm3) and b. log viral loads (copies/ml) for P1 (blue) and P2 (red) are shown. P1 and P2 were exposed to the same third party on day 0. P1 remained off therapy for 930 days post-exposure whilst P2 progressed more rapidly and commenced HAART 249 days post-exposure. Plasma for baseline sequencing was collected on day 63 but the CD4+ count or VL were not recorded. At day 245, P1 was diagnosed with acute HCV infection and had evidence of super-infection in plasma collected at day 235, having been exposed to a fourth person after day 63.