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Table 1 Superinfection resistance in cells infected with GALV or A-MLV

From: The receptors for gibbon ape leukemia virus and amphotropic murine leukemia virus are not downregulated in productively infected cells

Cell lines

Primary virus

Challenge virus

Infection by challenge virus (no. of blue foci)a

MDTF SLC20A1-HA

Not infected

GALV/βgal

2.1 × 106

  

A-MLV/βgal

1.9 × 106

 

GALV-GFP-C11D

GALV/βgal

4.2 × 102

  

A-MLV/βgal

1.6 × 106

 

SEATO

GALV/βgal

3.1 × 102

CHOK1 SLC20A2-HA

Not infected

A-MLV/βgal

3.4 × 106

 

A-MLV-GFP

A-MLV/βgal

5.3 × 102

 

4070

A-MLV/βgal

3.9 × 102

MDBK SLC20A2-HA

Not infected

A-MLV/βgal

1.1 × 105

  

GALV/βgal

3.6 × 105

 

A-MLV-GFP

A-MLV/βgal

<10

  

GALV/βgal

3.2 × 105

  1. aThe number of blue foci observed in cells in productively infected cells 48 hours after exposure retroviral vectors containing the lacZ gene (see Materials and Methods). This number represents the average titer obtained from two independent experiments.