Figure 5From: A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cellsSOSIP.R6-IZ-CD40L activates NF-κB through CD40. 293T-CD40 cells were incubated for 18h with mock supernatant or supernatant containing SOSIP.R6-IZ, SOSIP.R6-IZ-CD40L or IZ-CD40L after which SEAP activity in the supernatant was measured. Bars indicated are mean of two experiments + SEM.Back to article page