Figure 1From: Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infectionComparison of T cell recognition of index sequence and variant sequence peptides in IFNγ ELISPOT assays. In each patient, PBMC from the specified days following symptom onset were stimulated with log-fold titrations (between 10-4 and 10-10M) of index sequence peptide (closed diamonds) and the variant peptide(s) that evolved during the first year post-presentation (open squares and circles). The magnitude of the T cell response (IFNγ spot-forming cells per million PBMC) was measured at each peptide concentration.Back to article page