Env hypervariable loop amino acid diversity of SIVcpz Ptt -Cam155 clonal sequences in 2004 and 2009. The hypervariable loops V1, V2, V3 and V4 are analyzed. The alignment consensus of all clonal sequences is indicated at the top. The dots stand for gaps, dashes for the same amino acid as the consensus, the question marks in the consensus reveal no major amino acid in the alignment. On the left side, the clone names 040 to 049 and 090 to 099 stand for SIVcpzPtt-Cam155 clones from 2004 and 2009, respectively. The glycosylation consensus motifs (NXT/S) are highlighted in grey, important cysteines in red and the V3 crown in yellow stressing the switch from 2004 to 2009.