Env Mutants | Cell-Cell Fusion (%) | Surface Expression (mAb 902) (%) | Infectivity (pseudotyped) (%) | Virus-cell Fusion (%) | gp41 Incorporation (%) |
---|---|---|---|---|---|
WT | 100 | 100 | 100 | 100 | 100 |
A | 62 | 101 | 57 | 17 | 101 |
B | 41 | 195 | 16 | 0 | 8 |
C | 30 | 125 | 13 | 0 | 5 |
D | 31 | 120 | 4 | 17 | 9 |
E | 30 | 136 | 1 | 0 | 22 |
Y | 96 | 447 | 47 | 0 | 73 |
YA | 62 | 563 | 6 | 14 | 154 |
YB | 35 | 396 | 6 | 0 | 39 |
YC | 30 | 563 | 5 | 0 | 56 |
YD | 29 | 495 | 2 | 0 | 9 |
YE | 17 | 194 | 1 | 0 | 17 |