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Table 1 Summary of the Functional Properties of HIV-1 Env Mutants

From: Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity

Env
Mutants
Cell-Cell
Fusion
(%)
Surface
Expression
(mAb 902)
(%)
Infectivity
(pseudotyped)
(%)
Virus-cell
Fusion
(%)
gp41
Incorporation
(%)
WT 100 100 100 100 100
A 62 101 57 17 101
B 41 195 16 0 8
C 30 125 13 0 5
D 31 120 4 17 9
E 30 136 1 0 22
Y 96 447 47 0 73
YA 62 563 6 14 154
YB 35 396 6 0 39
YC 30 563 5 0 56
YD 29 495 2 0 9
YE 17 194 1 0 17