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Table 7 Cellular miRNAs with published effect on HIV-1 exhibited similar expression trends between indicated infections of CEMx174 lymphocytes

From: Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1

Expression Level for
Indicated Infection State Relative to Mock a
 
miRNA HIV-1 RSS ΔVV Targeted Transcript
and Expected Outcome
hsa-miR-17-5p 0.5 0.3 0.4 3'-UTR PCAF
(Triboulet 2007 [15])
hsa-miR-20a 0.6 0.2 0.5 Upregulation of cofactor
for Tat transcriptional
trans-activation, PCAF
hsa-miR-150 2.1 2.7 1. 8  
hsa-miR-382 1.7 1.1 1.4 HIV-1 3'-UTR
hsa-miR-125b 0.2 0.3 0.2 (Huang 2007 [16])
Promotion of viral latency
hsa-miR-28 <MD <MD <MD in resting T cells
hsa-miR-223 <MD <MD <MD  
hsa-miR-198 b 2.1 1.7 2.1 3'-UTR CCNT1
(Rice and Sung 2009 [62])
Downregulation of
cofactor for Tat
transcriptional trans-
activation, cyclin T1
  1. a Expression trends of indicated cellular miRNAs given for each viral strain relative to uninfected controls.
  2. b <MD: less than the minimum detectable signal.
  3. c Upregulation trend was validated by qRT-PCR on independent infections.