Table 5 Downregulation of selected miRNAs is diminished by RSS mutation
From: Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1
| Â | Downregulation Relative to Mock Infection a | Lessened Downregulation for RSS Relative to Indicated Infection b | |||
|---|---|---|---|---|---|
miRNA | HIV-1 | RSS | ΔVV | HIV-1 | ΔVV |
hsa-miR-10a | 26% | 43% | 32% | 17% | 10% |
hsa-miR-23a | 19% | 34% | 22% | 15% | 11% |
hsa-miR-25 | 27% | 43% | 15% | 17% | 28% |
hsa-miR-27a | 31% | 37% | 18% | 6% | 19% |
hsa-miR-30d | 34% | 54% | 30% | 20% | 25% |
hsa-miR-32 | 11% | 24% | 4% | 13% | 19% |
hsa-miR-92 | 33% | 50% | 33% | 17% | 17% |
hsa-miR-95 | 39% | 51% | 41% | 12% | 10% |
hsa-miR-99b | 46% | 53% | 33% | 7% | 20% |
hsa-miR-100 | 24% | 35% | 19% | 11% | 16% |
hsa-miR-103 | 46% | 53% | 37% | 6% | 16% |
hsa-miR-107 | 42% | 51% | 31% | 8% | 20% |
hsa-miR-125b | 16% | 26% | 19% | 10% | 7% |
hsa-miR-128 | 26% | 47% | 29% | 21% | 19% |
hsa-miR-135a | 23% | 35% | 18% | 12% | 17% |
hsa-miR-142-5p | 24% | 30% | 20% | 5% | 10% |
hsa-miR-148b | 37% | 49% | 39% | 12% | 10% |
hsa-miR-181a | 40% | 53% | 47% | 13% | 6% |
hsa-miR-186 | 50% | 64% | 50% | 14% | 14% |
hsa-miR-193a | 40% | 69% | 44% | 29% | 24% |
hsa-miR-369-3p | 27% | 41% | 39% | 14% | 2% |
hsa-miR-376a | 43% | 59% | 43% | 16% | 15% |
hsa-miR-379 | 40% | 61% | 47% | 21% | 14% |
hsa-miR-423 | 44% | 65% | 24% | 21% | 41% |
hsa-miR-601 | 31% | 38% | 21% | 7% | 17% |
hsa-miR-660 | 40% | 66% | 42% | 26% | 24% |
hsa-miR-671 | 36% | 47% | 46% | 11% | 0 |