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Table 4 Mature miRNAs that exhibit expression change by a factor of ≥2 between RSS and HIV-1 infection standardized to mock

From: Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1

  

RSS Relative to Mock a

  

Up

Unchanged

Down

 

Up

hsa-miR-494

hsa-miR-194

hsa-miR-500

-

HIV-1

    

Relative

Unchanged

-

hsa-miR-33b

hsa-miR-105b

hsa-miR-453

hsa-miR-499

hsa-miR-17-5p

hsa-miR-20a

hsa-miR-20b

hsa-miR-30e-3p

hsa-miR-106a

hsa-miR-219

to

    

Mock

Down

-

-

hsa-miR-21

hsa-miR-26b

hsa-miR-32

hsa-miR-215

hsa-miR-658

  1. a Nineteen miRNAs exhibited expression differences between the indicated strains relative to mock infection. The miRNAs indicated in plain font exhibited reduced expression by a factor of 2 or more for RSS compared to HIV-1. The three miRNAs in underlined font exhibited increased expression by 2-fold or more for RSS compared to HIV-1. Notably, miR550 upregulation by HIV-1 was attenuated in RSS infection (Table 3) but is excluded from Table 4 because miR550 was not detectable in cells lacking virus (mock infection).