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Table 4 Mature miRNAs that exhibit expression change by a factor of ≥2 between RSS and HIV-1 infection standardized to mock

From: Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1

   RSS Relative to Mock a
   Up Unchanged Down
  Up hsa-miR-494 hsa-miR-194
hsa-miR-500
-
HIV-1     
Relative Unchanged - hsa-miR-33b
hsa-miR-105b
hsa-miR-453
hsa-miR-499
hsa-miR-17-5p
hsa-miR-20a
hsa-miR-20b
hsa-miR-30e-3p
hsa-miR-106a
hsa-miR-219
to     
Mock Down - - hsa-miR-21
hsa-miR-26b
hsa-miR-32
hsa-miR-215
hsa-miR-658
  1. a Nineteen miRNAs exhibited expression differences between the indicated strains relative to mock infection. The miRNAs indicated in plain font exhibited reduced expression by a factor of 2 or more for RSS compared to HIV-1. The three miRNAs in underlined font exhibited increased expression by 2-fold or more for RSS compared to HIV-1. Notably, miR550 upregulation by HIV-1 was attenuated in RSS infection (Table 3) but is excluded from Table 4 because miR550 was not detectable in cells lacking virus (mock infection).