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Table 2 Distribution of changes in mature miRNA expression relative to uninfected lymphocytes for infection with indicated viral strain

From: Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1

 

Infection Relative to Mock a

Expression Trend b

HIV-1

RSS

ΔVV

Up

72

74

74

Down

106

104

111

No change

157

153

146

<MD

234

238

238

  1. a Human CEMx174 lymphocytes infected by co-culture with indicated virus were screened by miRNA microarray. The number of mature miRNA probes present on the chip was 518 after exclusion of four probes removed from miRBase. Values represent number of probes affected. b Up: upregulated (≥2.0 ×); Down: downregulated (≤0.5×); No change: between 0.5-2.0 ×; <MD: less than minimum detectable limits.