Figure 8From: Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domainInhibition of in vitro assembly by NYAD-201. (A) Negatively stained EM images of mature-like particles resulting from in vitro assembly of CA proteins in the presence of no peptide (Control), 0.25-, 0.5-, 1.0-, 3.0- and 5-fold molar equivalent of NYAD-201. (B) A dose-response effect of NYAD-201 on the tube-like mature particle formation. (C) In vitro assembly of CA proteins in the presence of no peptide (control) and 3-fold molar equivalent of NYAD-233.Back to article page