Figure 6
From: Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain
The 1H-13C HSQC spectra of CTD complexed with the peptide NYAD-203. (A) The methyl region of the free and peptide (25 μM) complexed [U C13, N15] CTD from the 1H-13C HSQC spectra is shown in the panel. (B) CTD residues perturbed upon binding to the peptide and could be assigned unambiguously are annotated (bold/black) in the structure. (C) The population weighted changes in the Cδ2 peak intensity of Leu190 from CTD in the free and bound states at four peptide concentrations.