Table 3 The impact of CCR2-CCR5 haplotypes on HIV-1 viral load in Zambian index partners and seroconverters

Viral Load Table for CCR5 haplotype/diplotype

Haplotype/diplotype

N

β ± SE^a

P*

N

β ± SE^a

P*

HHF*2

232

-0.21 ± 0.09

0.024

89

-0.10 ± 0.58

0.089

HHF*2/HHF*2

27

-0.08 ± 0.16

0.625

10

-0.70 ± 0.26

0.007

HHD (All)

164

-0.12 ± 0.06

0.052

69

0.24 ± 0.10

0.021

HHE (All)

131

0.13 ± 0.08

0.096

61

0.12 ± 0.12

0.339

HHD/HHE

18

-0.22 ± 0.20

0.270

16

0.49 ± 0.21

0.020

HHD/X (No HHE)

146

-0.11 ± 0.08

0.157

53

0.14 ± 0.13

0.284

HHE/X (No HHD)

113

0.19 ± 0.09

0.026

45

-0.06 ± 0.13

0.673

Multivariable Model for Interaction**

Haplotype/diplotype

N

β ± SE^a

P*

N

β ± SE^a

P*

HHD/X (No HHE or HHF*2)

109

-0.16 ± 0.09

0.560

37

0.24 ± 0.16

0.118

HHE/X (No HHD or HHF*2)

69

0.36 ± 0.11

0.002

31

0.10 ± 0.16

0.556

HHD/HHE

18

-0.16 ± 0.20

0.444

16

0.54 ± 0.22

0.014

HHF*2/HHF*2

27

-0.02 ± 0.16

0.918

10

-0.58 ± 0.26

0.027

HHF2/X (No HHD, HHE or HHF*2)

124

0.05 ± 0.09

0.602

49

0.10 ± 0.14

0.496