Table 1 Demographic, epidemiologic and virologic characteristics of the HIV-1 nontransmission and transmission serodiscordant Zambian couples

Number of couples

327

240

Male/Female (index partner)

148/179

147/93

0.0002

Age of partners (yrs)

Index

31.5 ± 7.9

30.6 ± 7.8

0.170

Exposed

32.0 ± 8.3

28.6 ± 7.3

< 0.0001

Follow-up time (median [IQR], months)

31.5 [17.0-56.1]

17.7 [8.8-36.2]

< 0.0001

Male circumcised

   Index

8.8%

9.0%

0.970

   Exposed

19.5%

9.9%

0.053

Genital ulcers

   Index

12.8%

36.6%

< 0.0001

   Exposed

4.1%

26.3%

< 0.0001

Genital inflammation ^a

   Index

10.3%

26.3%

< 0.0001

   Exposed

6.6%

29.1%

< 0.0001

Any sexually transmitted disease

Index

20.7%

50.2%

< 0.0001

Exposed

10.0%

46.0%

< 0.0001

HIV-1 RNA level (log₁₀) in index partner

4.47 ± 0.90

4.96 ± 0.70

< 0.0001

HIV-1 RNA level (log₁₀) in seroconverted partner

4.50 ± 0.80

NA