Table 7 Enriched pathways in CD4+ T cells from the LTNP group (BDL versus LTNP)
Gene set name | Gene set size | NES | NOM p-val | FDR |
|---|---|---|---|---|
MAPK pathway associated | Â | Â | Â | Â |
NTHIPATHWAY | 22 | -2.05 | 0.000 | 0.008 |
ST_JNK_MAPK_PATHWAY | 40 | -1.88 | 0.002 | 0.038 |
ST_GRANULE_CELL_SURVIVAL_PATHWAY | 26 | -1.77 | 0.002 | 0.049 |
IGF1PATHWAY | 20 | -1.77 | 0.002 | 0.049 |
INSULINPATHWAY | 21 | -1.79 | 0.004 | 0.050 |
NGFPATHWAY | 19 | -1.81 | 0.002 | 0.053 |
CARDIACEGFPATHWAY | 17 | -1.75 | 0.000 | 0.056 |
41BBPATHWAY | 18 | -1.74 | 0.014 | 0.058 |
CDMACPATHWAY | 16 | -1.71 | 0.010 | 0.073 |
HSA04012_ERBB_SIGNALING_PATHWAY | 87 | -1.70 | 0.008 | 0.074 |
SA_TRKA_RECEPTOR | 16 | -1.70 | 0.012 | 0.075 |
HSA04010_MAPK_SIGNALING_PATHWAY | 256 | -1.64 | 0.000 | 0.087 |
PDGFPATHWAY | 27 | -1.66 | 0.012 | 0.088 |
TPOPATHWAY | 23 | -1.66 | 0.012 | 0.089 |
EGFPATHWAY | 27 | -1.66 | 0.018 | 0.091 |
Cell signaling | Â | Â | Â | Â |
INFLAMPATHWAY | 29 | -1.99 | 0.000 | 0.017 |
CYTOKINEPATHWAY | 20 | -1.95 | 0.000 | 0.023 |
CCR5PATHWAY | 18 | -1.78 | 0.006 | 0.049 |
TCRPATHWAY | 43 | -1.80 | 0.006 | 0.052 |
IL6PATHWAY | 21 | -1.79 | 0.002 | 0.054 |
IL1RPATHWAY | 32 | -1.82 | 0.000 | 0.055 |
IL12PATHWAY | 20 | -1.68 | 0.018 | 0.083 |
TOLLPATHWAY | 34 | -1.66 | 0.012 | 0.086 |
HSA04060_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | 253 | -1.65 | 0.000 | 0.087 |
HSA04660_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 93 | -1.65 | 0.006 | 0.089 |
CALCINEURIN_NF_AT_SIGNALING | 92 | -1.92 | 0.000 | 0.030 |
Other | Â | Â | Â | Â |
HYPERTROPHY_MODEL | 17 | -1.91 | 0.000 | 0.025 |
ATMPATHWAY | 19 | -1.86 | 0.000 | 0.043 |
HSA05210_COLORECTAL_CANCER | 85 | -1.78 | 0.000 | 0.049 |
SMOOTH_MUSCLE_CONTRACTION | 140 | -1.83 | 0.000 | 0.051 |
CIRCADIAN_EXERCISE | 40 | -1.79 | 0.000 | 0.051 |
GPCRPATHWAY | 35 | -1.76 | 0.006 | 0.054 |
ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | 42 | -1.73 | 0.002 | 0.064 |
P53HYPOXIAPATHWAY | 19 | -1.68 | 0.022 | 0.082 |