Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease

Table 2 Number of differentially expressed genes in pairwise comparisons for CD4+ and CD8+ T cells (fold change > 2 and B-statistic > 0)

Differentially expressed genes	CD4		CD8		CD4 and CD8
	up	down	up	down	up	down
BDLvsNEG	50	24	206	72	15	3
VIRvsNEG	173	128	477	273	79	48
LTNPvsNEG	5	9	17	6	0	0
BDLvsLTNP	0	3	3	1	0	0
VIRvsLTNP	29	7	118	63	10	2
BDLvsVIR	1	8	5	12	0	1

Up: up-regulation; down: down-regulation; vs: versus; CD4 and CD8: genes differentially expressed in both CD4+ and CD8+ T cells in the same paired comparison.

ISSN: 1742-4690