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Table 1 Clinical symptoms observed after inoculation of macaques with different doses of PBj-wt or PBj-Nef202/203GG virus

From: Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease

Virus

Macaque

Dose (TCID50)

Anorexia

Dehydration

Haemor. Diarrhea

Apathy

Rash

PBj-wt

#260

5 × 106

+

+

+

+

-

 

#250

5 × 105

+

+

+

+

+

 

#6504

5 × 105

+

+

+

+

-

PBj-

Nef 202/203GG

#277

5 × 106

-

-

-

-

-

 

#267

5 × 105

-

-

-

-

-

 

#275

5 × 105

-

-

-

-

-

 

#276

5 × 105

-

-

-

-

-

  1. Occurrence of symptoms is indicated by "+", absence by "-".
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Retrovirology

ISSN: 1742-4690

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