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Table 1 Clinical symptoms observed after inoculation of macaques with different doses of PBj-wt or PBj-Nef202/203GG virus

From: Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease

Virus Macaque Dose (TCID50) Anorexia Dehydration Haemor. Diarrhea Apathy Rash
PBj-wt #260 5 × 106 + + + + -
  #250 5 × 105 + + + + +
  #6504 5 × 105 + + + + -
PBj-
Nef 202/203GG
#277 5 × 106 - - - - -
  #267 5 × 105 - - - - -
  #275 5 × 105 - - - - -
  #276 5 × 105 - - - - -
  1. Occurrence of symptoms is indicated by "+", absence by "-".