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Figure 7 | Retrovirology

Figure 7

From: Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers

Figure 7

Impaired proliferation of Tax-specific but not CMVpp65-specific CD8+ T-cells in sATL patients. For antigen-specific T-cell proliferation, PBMCs from sATL (#110; square, #353; triangle) and cATL (#224; circle) patients were cultured for 13 days with 100 nM Tax (A) or CMV (B) peptide. Each dot indicates the percentage of tetramer+ cells in CD8+ T-cells at day 0 and day 13 after culture. Clinical information on ATL patients used here is as follows; sATL#110: age; 40 s, gender; F, WBC#; 11,000/μL {lymphocyte (lym); 39%, abnormal lymphocytes (ably); 4%}, cATL#224: age; 50 s, gender; F, WBC#; 7900/μL (lym; 30%, ably; 33%), sATL#353: age; 60 s, gender; M, WBC#; 4620/μL (lym; 39%, ably; 5%).

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