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Figure 6 | Retrovirology

Figure 6

From: Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers

Figure 6

Conserved functions of CMV-specific CD8+ T-cells in AC#287. (A) For antigen-specific T-cell proliferation, PBMCs from #287 were cultured for 13 days with or without 100 nM CMV peptide. The number indicates the percentage of CMV tetramer+ cells in CD8+ T-cells. (B-D) PBMCs were stimulated with or without 10 μM CMV peptide for 6 hrs. IFN-γ production (B), CD69 (C) and CD107a (D) expression of CMVpp65-specific CD8+ T-cells in #287 was analyzed by flow cytometry. (B, D) The number represents the percentage of the indicated marker-positive cells in CMVpp65-specific CD8+ T-cells. (C) Bar indicates the percentage of CD69+ cells in CMV-specific CD8+ T-cells.

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