IFN-γ production and cell proliferation of Tax-specific CD8+ T-cells in ACs. (A, B) IFN-γ production (A) and cell proliferation (B) of Tax-specific CD8+ T-cells in PBMCs from 4 ACs were assessed as in Figure 2. The number given in parenthesis shows mean fluorescence intensity (MFI) of IFN-γ expression in the IFN-γ+ tetramer+ cells. (C, D) Relation between the percentage of IFN-γ+ (C) or dividing (D) Tax-specific CD8+ T-cells and proviral loads (PVL) in ACs. Dots represent individual ACs. The Spearman rank correlation test was used to determine correlations and P values.