Skip to main content

Table 5 Kinetic data for the interaction of GNA and GNAmaize with immobilized HIV-1 IIIB gp120

From: Differences in the mannose oligomer specificities of the closely related lectins from Galanthus nivalis and Zea maysstrongly determine their eventual anti-HIV activity

 

KD(nM)

ka(1/Ms)

kd(1/s)

GNA vs III B gp120 (CHO)

0.33 ± 0.07

(2.81 ± 0.68) E+06

(9.00 ± 1.14) E-04

GNA vs III B gp120 (Baculovirus)

0.17 ± 0.12

(2.75 ± 1.56) E+06

(3.63 ± 0.75) E-04

GNA maize vs III B gp120 (CHO)

34 ± 13

(1.37 ± 0.78) E+05

(5.24 ± 4.50) E-03

GNA maize vs III B gp120 (Baculovirus)

77 ± 17

(2.23 ± 0.74) E+04

(1.64 ± 0.20) E-03