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Figure 3 | Retrovirology

Figure 3

From: Differences in the mannose oligomer specificities of the closely related lectins from Galanthus nivalis and Zea maysstrongly determine their eventual anti-HIV activity

Figure 3

Kinetic analysis of the interactions of GNA maize (A, C) and GNA (B, D) with immobilized HIV-1 III B gp120 isolated from CHO cell cultures and from Baculovirus using SPR technology. Serial two-fold analyte dilutions (covering a concentration range from 5 to 80 nM and from 39 to 625 nM, respectively) were injected over the surface of the immobilized gp120. The experimental data (coloured curves) were fit using the 1:1 binding model (black lines) to determine the kinetic parameters. The data are a representative example of three independent experiments. The biosensor chip density was 822 RU for gp120 from CHO (or 6.9 fmol gp120) (panels A & B) and 725 RU for gp120 from Baculovirus (or 6.0 fmol gp120) (panels C & D).

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Retrovirology

ISSN: 1742-4690

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