Outcome of first line antiretroviral therapy (art) with respect to treatment Failure at ART CENTRE, B. J. Medical College, Civil Hospital, Ahmedabad

Background

To Study outcome of 1^st Line Anti Retroviral Therapy (ART) at with respect to treatment failure at ART Centre, B. J. Medical College, Civil Hospital, Ahmedabad, Gujarat, India.

Methods

All the ever started 1^st Line ART patients were evaluated for treatment failure as per Indian National ART Guidelines at our institute.

Results

ART Centre, B. J. Medical College, Civil Hospital was started on 25^th April, 2005. Till October 2009 ever registered patients are 11827 among this total 5847 patients were initiated ART as per Indian National ART Guidelines, Table 1.

Table 1

Discussion

The clinical goals of HIV treatment are optimally accomplished through consistent high-level adherence to Highly Active Anti Retroviral Therapy (HAART) and sustained virological suppression through cost effective regimen (2NRTIs+1NNRTI). At the end of more than 4 years total suspected IF patients are only 73 (2.13%) of which only 49 (1.70%) has actual virological failure; shows the efficacy of the 1^st Line ART. Failure to access care and discontinuation of or non-adherence to ART are the most important factors associated with the progression of HIV disease.