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Figure 3 | Retrovirology

Figure 3

From: Polymorphisms of HIV-2 integrase and selection of resistance to raltegravir

Figure 3

Positions selected in vitro under RAL pressure in an HIV-2 integrase 3D model. A 3D-model of the HIV-2 integrase (pdb: 3F9K) was modified using the ViewerLite software. The residues involved in IN enzymatic activity were highlighted, as well as positions 91 and 175, which were mutated under RAL pressure. The N-terminal and catalytic domains are represented as: A. Line ribbons; B. Sticks; C. Molecular surface.

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