Figure 4From: The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope proteinThe immunoblotting analysis of wild type (WT) and Ala-inserted mutant Env. The envelope proteins expressed in COS-7 cells transfected with the Env expression vector were detected with anti-gp120 antibody (for gp160 and gp120) or with anti-gp41 antibody. The results of single- and multiple-Ala-insertion mutants are shown in (A) and (B), respectively.Back to article page