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Figure 6 | Retrovirology

Figure 6

From: Misfolding of CasBrE SU is reversed by interactions with 4070A Env: implications for gammaretroviral neuropathogenesis

Figure 6

CasBrE SU mediates virus entry via the ecotropic receptor. Viral supernatants taken from 4070A-infected hrGFP-, CasES-, and CasE-NSCs were titered on NIH 3T3 fibroblasts cells with (black bars) and without (white bars) 4070A infection. The 4070A infection acts as a means to interfere with virus entry via the amphotropic receptor, PiT-2. CasBrE Env+ foci were detected using monoclonal antibody 697 and hrGFP foci were detected by direct viewing of target cell fluorescence. Assays were run in triplicate and error bars represent the standard deviation of the log of the vector titers.

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Retrovirology

ISSN: 1742-4690

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