Figure 3

Box-and-whisker plots of genetic diversity of the dissected envelope gene for V1, V2, C2, V3, C3, V4, C4 and V5 and gp41 for slow progressors and progressors. The whiskers extend to the upper and lower adjacent values. Comparisons between the groups were done with the Mann Whitney unpaired t test, and p values are shown. Correlations were regarded as statistically significant with a p value < 0.05 and only significant p values are shown. p values depicted with an asterisk (*) indicate the ones corrected for multiple comparisons using the Bonferroni correction of p ≤ 0.006. Mean diversity value is depicted as (+). Figure 3A Diversity of V1, V2, C2, V3, C3, V4, C4, V5 and gp41 in slow progressors (SP) and progressors (P) overall. Figure 3B Box and whisker plots of intra-patient diversity analysis for slow progressors for different regions of the Env gene for study entry and study exit. Figure 3C Box and whisker plots of intra-patient diversity analysis for progressors for different regions of the Env gene for study entry and study exit.