Relative replication capacity of phenotypic SIV variants during primary infections differs with route of inoculation

Table 1 Summary of the phenotypes of the SIV variants.

Virus Type	Name	In vivopathogenesis		In vitroReplication Capacity
		Relative Viral Load^#	CD4⁺T cell decline	Infectivity	Co-stimulated Lymphoblasts	Macrophages	Dendritic Cells	Resting CD4⁺T Cells	DC-T Cell Co-cultures
Early	SIVmneCl8	1/1	Slow	Low	Low	Moderate	ND*	ND	Low
Late	SIVmne027	30/4000	Rapid	High	High	Low	ND	Low	High

^#Differences in plasma viral loads during the acute and chronic stages (acute/set-point) following intravenous inoculation are indicated relative to SIVmneCl8.
*ND, not detected
References describing the variant viruses: [21, 22, 27, 34, 41, 62–67]

ISSN: 1742-4690