Skip to main content

Advertisement

Table 2 RT inhibitor susceptibilities for HIV-1 subtype B and subtype C viruses

From: Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C

RT inhibitors EC50(nM)a
  Subtype B HIV-1 Subtype C HIV-1
ZDV 12.9 ± 5.9 34.8 ± 12.9
3TC 45.4 ± 16.4 105.9 ± 40.2
TFV 334.8 ± 140.9 304.8 ± 93.1
NVP 50.2 ± 29.6 170.4 ± 79.5
EFV 0.6 ± 0.2 1.3 ± 0.4
ETR 0.9 ± 0.4 0.5 ± 0.01
  1. a Data represent means ± standard deviations of three determinations.