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Figure 4 | Retrovirology

Figure 4

From: Hematopoietic stem cells and retroviral infection

Figure 4

The Role of HTLV-1 Infection of HSCs: Potential Mechanisms for Generation of an Infectious Leukemic Stem Cell (ILSC/ICSC). HTLV-1 infection and subsequent Tax1 expression can lead to either cell cycle arrest or generation of pre-leukemic stem cells (pre-LSC/CSC) from infected CD34+ hematopoietic progenitor and stem cells (HP/HSCs).

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