Viral dynamics in SIV-infected macaques receiving a short-term HAART just after the viremia peak. Among 8 animals infected since 14 days, 5 animals received the AZT/3TC/IDV combination (HAART d14-d28: black symbol) for 14 days whereas 3 animals received a placebo (placebo d28: open symbol) for the same period. All the animals were killed at the end of treatment (28 days pi). HAART initiated at 14 days pi conducted to a significant reduction of PVL (a) but a non significant decrease of CVL (b). Viral dissemination (c) and replication (d,e) were reduced at different levels depending on the tissue considered: in the gut, the decrease was significant, whereas in spleen and peripheral LN, the viral dissemination and replication were almost maintained. *: indicated a significant difference (p < 0.05) and t a trend (0.05 < p < 0.06) using a Mann-Whitney test. LN: lymph node, G mean: geometric mean. The grey area indicates the quantitative threshold of our qRT-PCR and qPCR assays.