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Table 3 Neutralization sensitivity of patient envelopes to autologous plasma antibodies

From: Variations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade C envclones obtained at different time points from antiretroviral naïve Indian patients with recent infection

Envclones

Baseline plasma

Plasma First visit (F1)

Plasma Second visit (F2)

2.J8

601

228

<20

2.J9

522

240

<20

2-3.J4

350

<20

<20

2-3.J7

374

<50

<20

2-3.J17

300

<20

<20

2-3.J18

<20

540

652

2-5.J3

<50

<20

<20

2-5.J11

50

<20

<20

3.J16

195

696

2389

3-3.J9

349

554

1053

3-5.J25

<20

<20

184

3-5.J38

<20

<20

72

4.J2

421

2671

3848

4.J22

87

811

1172

4.J27

74

773

871

4-2.J41

103

98

406

4-2.J45

3375

6287

8307

4-2.J42b

60

<20

115

4-2.J45b

70

<50

500

4-2.J46b

<50

<50

160

4-2.J47b

72

<50

340

4-5.J5

64

<20

244

5.J41

<20

110

1934

5-3.J2

<20

<20

1845

5-3.J4

<20

<20

1067

5-3.J5

<20

<20

1161

5-3.J9

<20

<20

1104

5-4.J16

<20

<20

<50

5-4.J18

<20

<20

<50

5-4.J22

<20

<50

223

5-4.J49

<20

<50

180

11.J25

66

2158

2830

11.J28

76

2008

2310

11-3.J3

<20

<50

1193

11-3.J9

<20

<20

148

11-3.J16

<20

<20

201

11-5.J12

<20

<20

<50

  1. Values are reciprocal titer of patient plasma resulting 50% reduction in relative luminescence unit (RLU) as an indicator of neutralization sensitivity in TZM-bl cells following infection with pseudoviruses with 200TCID50. The ID50 values are average of two independent assays wherein each assay was done in duplicates.
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Retrovirology

ISSN: 1742-4690

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