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Figure 4 | Retrovirology

Figure 4

From: Broader HIV-1 neutralizing antibody responses induced by envelope glycoprotein mutants based on the EIAV attenuated vaccine

Figure 4

Neutralizing antibody titers against HIV-1 of immunized guinea pigs' sera. End-point neutralizing antibody titers of HIV-1 by sera from mock-, gp145- and gp145-10M-immunized guinea pigs. Sera were collected at six weeks after the last immunization for testing. The neutralizing experiment was conducted by using a panel of clinical isolates in PBMC cells (a) and a panel of tier 2-3 peudeovirus in TZM-b1 cells (b). The 50% inhibitory dose (ID50) was defined as the plasma dilution.

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