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Table 1 CTL escape of breast milk and blood virus quasispecies at the Tat TL8 epitope during acute SIV infection.

From: Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys

 

Days after SIV infection

Animal #

Day 14

Day 18

Day 21

Day 28

206

blood

100%a (17/17)b

14.3% (3/21)

0% (0/26)

NDc

 

milk

100% (30/30)

87.5% (28/32)

17.4% (4/23)

0% (0/17)

257

blood

100% (29/29)

90.9% (20/22)

38.5% (10/26)

0% (0/20)

 

milk

100% (21/21)

100% (30/30)

54.5% (12/22)

0% (0/31)

402

blood

100% (28/28)

12.5% (3/24)

7.7% (2/26)

ND

 

milk

100% (18/18)

31.0% (9/29)

16.7% (1/6)

0% (0/32)

403

blood

100% (29/29)

54.2% (13/24)

9.4% (3/32)

ND

 

milk

100% (23/23)

47.6% (10/21)

17.4% (4/23)

0% (0/31)

  1. a % reported is the proportion of virus quasispecies that did not have an amino acid substitution within the Tat TL8 epitope (remained wild type).
  2. b In parentheses is the number of virus quasispecies that remained wild type at the Tat TL8 epitope/number of virus quasispecies sequenced.
  3. c ND = not done