Skip to main content
Figure 1 | Retrovirology

Figure 1

From: Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness

Figure 1

Virological and immunological characteristics of patient L. (A) Plasma viral load (diamonds) and CD4 + T-cell counts (triangles) of patient L from October 2005 till June 2007. An arrow indicates the probable time of HIV-1 superinfection. Biological clones were generated from PBMC samples collected in November 2005 and January 2006, respectively. (B) NJ tree constructed with representative nucleotide sequences derived from HIV-1 env-V3 obtained from plasma collected from patient L. Separate clusters formed by strains B1 and B2 are indicated. Env sequences from biological clones are indicated with clone numbers. Symbols in the tree correspond to samples from November 2005 (circles), January 2006 (diamonds) and April 2006 (squares). Reference sequences were HIV-1 strain HXB2 and subtypes C and D strains, respectively. The scale bar indicates the nucleotide distance between the sequences (as calculated with the Tamura-Nei method [59]).

Back to article page