Figure 4From: A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5αViral growth in the presence of TRIM5α. CEMss cells were infected with recombinant Sendai virus (SeV) expressing CM (black diamonds), human (gray circles), or CM-SPRY (-) (white diamonds) TRIM5α. Nine hours after infection, cells were superinfected with the indicated HIV-1 derivatives. Culture supernatants were separately assayed for levels of p24. Error bars show actual fluctuations between levels of p24 in duplicate samples. A representative of three independent experiments is shown.Back to article page