Transcriptome analysis of monocyte-HIV interactions

Retrovirology

Table 5 Functional classification of differentially expressed genes in monocytes of therapy-naïve and HIV patients

Immune function: chemotaxis	Immune function: inactivation	Immune function: activation	Anti-apoptotic (cis)	Pro-apoptotic (trans)	Cell cycle	Protein trafficking	Transcriptional regulation	Metabolic dysregulation
CCL23	ADORA2A	IL1F7	ADORA2A [80]	IL8 [81]	CCL23 [82]	CAPG	MAFF	CCR2 [65]
CCL4L1	LILRB4	PLA2G7	BCL6 [83]	HLA-DRA [50]	IL8 [84]	BCL6	NR0B2	NR0B2 [64]
CCR2		SLC11A1	CCL2 [85]	STAT1 [86]	NR0B2 [47]	MARCKS	BCL6	PLA2G7
CX3CR1		BCL6	CDKN1A [87]		BCL6 [88]	YWHAZ	CDKN1A	NAMPT [66, 67]
CXCL2		CD83	NAMPT [89]		CCL2		KLF10
IL8		IFI30	YWHAZ [90]		CDKN1A [91]		STAT1
		NAMPT			HLA-DRA [50]
		PTGER2			KLF10 [92]
		STAT1			NAMPT
					PDGFC
					STAT1 [55]

Official Gene Symbols are shown; genes in italics are downregulated, genes in boldface are upregulated.

ISSN: 1742-4690