Modulation of viral infectivity of the lab-attenuated strain HIV
by the secreted factors CCL2, NAMPT and PDGFC: infection of A) PBMC and B) MDM (pre-)treated with recombinant factors by HIV
. C) Modulation of the viral infectivity of the biological clones HIV968-2 and HIV968-3 by the secreted factor NAMPT in PBMC and MDM. TCID50 values were determined using the method of Reed & Muench, based on p24 measurement in culture supernatants. Infectivity in treated cells is expressed as a percentage of infectivity in untreated control cells. Results in 3 independent donors are shown.