Retrovirology

Table 1 Subject Details: Viral Load, CD4 counts and envelope PCR

From: Modulation of HIV-1 macrophage-tropism among R5 envelopes occurs before detection of neutralizing antibodies

MM1	Day^a	21	28	48	84	195	494	833	1231	1879	2702
	VL^b	81,000	34,400	14,900	5,400	60,000	63,400	169,300	32,100	111,600	22,200
	CD4^c	880	nd^d	nd	1000	nd	660	830	740	690	530
	env PCR^e		DNA		DNA			RNA			RNA
MM4	Day	17	52	108	206	297	493	574	844	1058	1191
	VL	160,000	9,900	42,300	30,200	24,000	19,900	34,500	137,200	nd	233,400
	CD4	nd	990	590	750	610	690	610	650	nd	490
	env PCR	DNA					RNA		RNA
MM8	Day	12	32	49	81	200	333	608	810	957
	VL	5,927,000	nd	454,100	41,900	59,000	44,500	41,800	105,200	154,800
	CD4	290	nd	610	350	410	420	260	240	90
	env PCR	DNA	DNA					RNA		RNA

a. Days counted from onset of symptoms characteristic of primary HIV infection (fever, myalgias, lethargy, a sore throat, headaches, anorexia, diarrhea).
b. VL, plasma viral load (RNA copies/ml) determined using Chiron 3.0 (Emeryville, Cal. USA).
c. CD4, CD4 cell numbers (cells/μl).
d. nd, not determined.
e. DNA or RNA source of envelope PCR.

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ISSN: 1742-4690

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