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Figure 4 | Retrovirology

Figure 4

From: Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivoescape from neutralising antibody

Figure 4

Sensitivity of A613 Env variants with distinct receptor usages to antagonists of the virus-receptor interaction. HIV(FIV) luciferase pseudotypes bearing the B14, B19, B28, B30, B31 and B32 Envs were examined for sensitivity to antagonism by anti-CD134 (A), sFc-CD134 (B, D, E) or sFc-TNC-CD134L (C). Infections were performed on MYA-1 cells (A-C), MCC-CD134 (D) or MCC control (E). (E) Pre-incubation with sFc-CD134 did not facilitate CD134-independent infection of MCC control cells. Each point represents the mean of triplicate estimations and is expressed as percent infection relative to no antagonist control. Each graph is typical of at least two independent experiments.

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Retrovirology

ISSN: 1742-4690

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