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Table 2 Lack of correlation between IL-10, IL-22 and CRP production and disease progression

From: High systemic levels of interleukin-10, interleukin-22 and C-reactive protein in Indian patients are associated with low in vitroreplication of HIV-1 subtype C viruses

 

IL-10

 

IL-22

 

CRP

 
 

r

(95% C.I.)§

p

r

(95% C.I.)

p

r

(95% C.I.)

p

Viral load

0.213

(-0.004 - 0.411)

ns¶

0.118

(-0.102 - 0.327)

ns

0.010

(-0.207 - 0.226)

ns

CD4 count

-0.146

(-0.349 - 0.071)

ns

-0.073

(-0.283 - 0.144)

ns

0.018

(-0.197 - 0.231)

ns

AIDS-defining illnessa

      

   Pulmonary TB†

0.041

(-0.174 - 0.252)

ns

-0.005

(-0.218 - 0.207)

ns

-0.054

(-0.264 - 0.161)

ns

Cryptosporidiosis+;

isosporiasis

0.165

(-0.05 - 0.364)

ns

0.178

(-0.037 - 0.377)

ns

0.085

(-0.13 - 0.293)

ns

   Wasting syndrome

0.122

(-0.094 - 0.326)

ns

0.101

(-0.115 - 0.307)

ns

0.161

(-0.054 - 0.362)

ns

   Lymphoma

-0.089

(-0.297 - 0.126)

ns

0.096

(-0.12 - 0.303)

ns

-0.022

(-0.234 - 0.192)

ns

Other clinical Sx‡

      

   F.U.O.⋇

0.158

(-0.057 - 0.359)

ns

0.098

(-0.118 - 0.305)

ns

0.039

(-0.176 - 0.250)

ns

   Chronic Diarrheao

0.172

(-0.043 - 0.371)

ns

0.388

(0.191 - 0.555)

<0.001

0.168

-0.047 - 0.231

ns

Constitutional

symptoms

0.015

(-0.199 - 0.227)

ns

0.033

(-0.181 - 0.244)

ns

-0.093

(-0.3 - 0.123)

ns

  1. § r, Spearman correlation coefficient; 95% C.I., 95% confidence interval.
  2. ¶ ns, not significant (overall p-value of more than 0.05).
  3. aClinical conditions listed in the AIDS surveillance case definition; only the most frequent in our study sample are shown.
  4. † Pulmonary TB, pulmonary tuberculosis.
  5. +Chronic, intestinal (> 1 month)
  6. ‡ Other clinical syndromes, non AIDS defining.
  7. ⋇ F.U.O., Fever of Unknown origin.
  8. oIdiopatic diarrhea, > 1 month.