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Table 1 Detection of lymphoma and FeLV in tissues collected upon necropsy from cat #261.

From: Dominance of highly divergent feline leukemia virus A progeny variants in a cat with recurrent viremia and fatal lymphoma

Tissue

Lymphoma (Histology)

In situHybridization

Immunohistology

  

gp70

p27

gp70

p27

p15E

Salivary glands:

      

- Mandibular

-

-

-

-

-

-

- Parotid

-

-

-

-

+

-

Duodenum

+ in GALT

+/++

+/++

-

-

-

Jejunum

+ in GALT

-

-

-

-

-

Ileum

+ in GALT

++ in GALT

++ in GALT

-

-

-

Colon

+ in GALT

+/++

+/++

-

-

-

Rectum

+ in GALT

+

+

-

-

-

Liver

+ (mainly centro-acinous)

++

++

-

-

-

Spleen

+

nt

nt

nt

nt

nt

Thymus

+

++

++

-

-

-

Tonsil

+

+/++

+

-

-

-

Lymph nodes:

      

- Sternal

+

++

++

-

-

-

- Popliteal

+

+/++

+/++

-

-

-

- Submandibular

+

+/++

+/++

-

-

-

- Mesenteric

+

+/++

+/++

-

-

-

Bone marrow

+

+

+

-

-

-

Kidney

+

+/++

++

-

-

-

Urinary bladder

+

++

++

-

-

-

Brain

-

-

-

-

-

-

Spinal cord

-

-

-

-

-

-

Ischiatic nerve

-

-

-

-

-

-

Muscle upper hind leg

-

nt

nt

nt

nt

nt

Lung

+ (foci)

+

+

-

++

-

Myocardium

-

-

-

-

-

-

Aorta

-

-

-

-

-

-

Diaphragm

+

+

+

-

-

-

Thyroid and parathyroid glands

-

-

-

-

-

-

  1. Lymphoma diagnosed by macroscopic and histological examination and FeLV detected by in situ hybridization and immunohistology. GALT = gut associated lymphoid tissue; nt = not tested; - = negative reaction; + = positive reaction; ++ = strong positive reaction; +/++ = positive or strong positive reaction depending on tissue section/cell type